The Science Behind Ipamorelin and CJC-1295

Written by Johnathon Anderson, Ph.D., a research scientist, and Associate Professor at the University of California Davis School of Medicine 

What Are Ipamorelin and CJC-1295?

Ipamorelin and CJC-1295 are peptides that signal to the pituitary gland to make more growth hormone in the body. These peptides are derived from small proteins naturally found in tissues.

Do Ipamorelin and CJC-1295 Influence Myotubule Physiology?

Ipamorelin and CJC-1295 contribute to myotubule augmentation via IGF-1 signaling pathways. IGF-1 plays a critical role in myotubule formation via the well-studied PI3K/Akt signaling pathway, among others. (17,18)

Do Ipamorelin and CJC-1295 Effect Collagenous Fibrils?

Ipamorelin and CJC-1295 regulate formation of collagenous fibrils. (32)

They have also been shown to influence elastin fiber formation via IGF-1 signaling pathways. (43–48)

References

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